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Lexapro



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Active ingredient - escitalopram oxalate.
Pharmacological properties.
Lexapro or lexapro generic is an antidepressant, selective serotonin reuptake inhibitor (SSRI). Inhibition of serotonin reuptake leads to increased concentrations of this neurotransmitter in the synaptic cleft, strengthens and prolongs its action on the postsynaptic receptor sites.
Absorption is independent of food intake. The bioavailability of lexapro is about 80%. The average time to reach maximum plasma concentration (Tmax) is 4 hours after multiple applications. The half-life (T ½) after multiple applications is about 30 hours.
Lexapro or lexapro generic and its main metabolites are excreted by the liver (metabolic pathway) and the kidneys. Most of them excreted as metabolites in the urine.
In the elderly (65 years) lexapro excreted slower than in younger patients.

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Indications.
Depressive episodes of any severity.
Panic disorder with / without agoraphobia.
Social anxiety disorder (social phobia).
Generalized anxiety disorder.

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Contraindications.
Hypersensitivity to the drug or its components, childhood and adolescence (18 years), concomitant with inhibitors of monoamine oxidase (MAO). Pregnancy, breast-feeding.
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Dosage.
Lexapro or lexapro generic administered orally once daily without regard to meals.
Depressive episodes.
Usually prescribe lexapro 10 mg once a day. Depending on individual patient response the dose may be increased to the maximum - 20 mg / day.
Antidepressant effect usually develops 2-4 weeks after starting treatment. After the disappearance of symptoms of depression for at least another 6 months necessary to continue therapy to consolidate the obtained effect.
Panic disorder with / without agoraphobia.
During the first week of treatment recommended dose is lexapro 5 mg / day, which is then increased to 10 mg / day. Depending on individual patient response the dose may be increased to the maximum - 20 mg / day.
The maximum therapeutic effect is achieved in about 3 months after starting treatment. Therapy lasts several months.
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Social anxiety disorder (social phobia).
Usually prescribe 10 mg once a day. Weakening of symptoms usually occurs within 2-4 weeks after starting treatment. Depending on individual patient response dose can then be reduced to 5 mg / day. or increased to the maximum - lexapro 20 mg / day. Because social anxiety disorder is a disease with a chronic course, the minimum recommended duration of the therapeutic course is 12 weeks. To prevent recurrence of the disease the drug can be administered for 6 months or longer depending on individual patient response.
Generalized anxiety disorder.
The recommended initial dose - 10 mg once a day. Depending on individual patient response the dose may be increased to the maximum - 20 mg / day.
Allowed long-term administration of the drug (6 months or longer) at a dose of 20 mg / day.
Elderly patients (over 65).
It is recommended to use half the usual recommended dose and a lower maximum dose (10 mg / day).
Decreased renal function.
In mild and moderate renal impairment adjustments of doses are required. Patients with severe renal insufficiency (CLCR below 30 ml / min) Lexapro or lexapro generic should be prescribed with caution.
Reduced liver function.
In mild and moderate hepatic impairment the recommended initial dose for the first two weeks of treatment is 5 mg / day. Depending on individual patient response the dose may be increased to 10 mg / day.
Discontinuation of treatment.
Upon termination of treatment by Lexapro dose should decrease gradually over 1-2 weeks to avoid withdrawal symptoms.

Lexapro online. Side effects.
Side effects most often occur on the first or second week of treatment and then tended to become less intense and less likely to occur with continued therapy.
From the side of the psyche: decreased libido, anorgasmia (in females).
The nervous system: insomnia or drowsiness, dizziness, and rarely observed violations of taste and sleep disturbance.
The respiratory system: sinusitis, yawning.
Part of the digestive system: nausea, diarrhea, and constipation.
For the skin: excessive sweating.
Part of the reproductive system: impotence, abnormal ejaculation.
Part of the body as a whole: weakness, pyrexia.
Metabolic disorders and eating disorders: anorexia.

Overdose.
Read before buy lexapro.
Symptoms.
Dizziness, tremor, agitation, drowsiness, confusion, seizures.
Treatment .
A specific antidote does not exist. Treatment is symptomatic and supportive: gastric lavage.

Product type.
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